Multidirectional Filamented Light Biofabrication Creates Aligned and Contractile Cardiac Tissues
Researchers at ETH Zurich, led by Prof. Robert Katzschmann, have pioneered a biofabrication technique for creating 3D cardiac tissues that closely replicate native myocardial tissue. By controlling the directionality and density of cardiac cells in 3D tissues, we’re setting new standards for cardiac biofabrication. This could have transformative applications in regenerative medicine and biohybrid robotic system.
Researchers at ETH Zurich, in collaboration with the EMPA and the University of Zürich, have pioneered a biofabrication technique for creating 3D cardiac tissues that closely replicate native myocardial tissue. This innovation, developed in collaboration with researchers including Lewis S. Jones, Miriam Filippi, Mike Yan Michelis, Aiste Balciunaite, Oncay Yasa, Gal Aviel, Maria Narciso, Susanne Freedrich, Melanie Generali, Eldad Tzahor, and Robert K. Katzschmann, addresses key challenges in tissue engineering by producing high-density cardiac tissues with controlled, multidirectional cellular alignment and specialized contractile properties.
Published in Advanced Science, this study showcases Multidirectional Filamented Light Biofabriction for creating aligned and contractile cardiac tissues. This biofabrication technique enables us to create more complex tissue structures, such as multi-layered cardiac tissues. This structure is similar to the natural alignment of the heart muscle. The approach holds promise for future applications in regenerative medicine and biohybrid robotics.
Read the Full Publication
To explore the complete findings and implications of this research, read the full article published in Advanced Science:
external page https://onlinelibrary.wiley.com/doi/epdf/10.1002/advs.202404509
Stay tuned for more updates as our team continues to push the boundaries of Bio-hybrid robotics technology and their applications.
